Coupled endo-exodeoxyribonuclease activity from HeLa cell nuclei interacts with specific regions of the SV40 mini chromosome.

@article{Quarless1985CoupledEA,
  title={Coupled endo-exodeoxyribonuclease activity from HeLa cell nuclei interacts with specific regions of the SV40 mini chromosome.},
  author={S. Quarless},
  journal={Biochemical and biophysical research communications},
  year={1985},
  volume={126 2},
  pages={
          805-11
        }
}
  • S. Quarless
  • Published 1985
  • Biology, Medicine
  • Biochemical and biophysical research communications
  • A recently described endo-exodeoxyribonuclease activity (1) was determined to interact preferentially with the origin/enhancer region and the 5' end of the late promoter region of the SV40 mini chromosome. The enzymatic activity has no preferential site of interaction with naked DNA, which suggests, the chromatin organization is responsible for this site directed interaction. 

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