Coupled endo-exodeoxyribonuclease activity from HeLa cell nuclei can function in an excision repair mode in vitro.
@article{Quarless1985CoupledEA, title={Coupled endo-exodeoxyribonuclease activity from HeLa cell nuclei can function in an excision repair mode in vitro.}, author={S. Quarless}, journal={Biochemical and biophysical research communications}, year={1985}, volume={126 2}, pages={ 812-7 } }
A single strand specific coupled endo-exodeoxyribonuclease activity has been purified and characterized from the nuclei of HeLa cells(7). The novelity of this activity is in the nature of its associated endo and exonuclease activities. Due to this aspect the ability of this activity to work in unison with DNA polymerase molecules in the process of DNA repair synthesis was investigated.
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References
SHOWING 1-6 OF 6 REFERENCES
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.
- Biology, Medicine
- Journal of molecular biology
- 1977
- 8,325
Purification of deoxyribonucleic acid polymerase delta from calf thymus: partial characterization of physical properties.
- Chemistry, Medicine
- Biochemistry
- 1980
- 52
Involvement of DNA polymerase alpha in simian virus 40 DNA replication.
- Medicine, Chemistry
- The Journal of biological chemistry
- 1978
- 141
Mouse DNA polymerase alpha. Subunit structure and identification of a species with associated exonuclease.
- Biology, Medicine
- The Journal of biological chemistry
- 1979
- 75