Counting integral numbers of amino acid residues per polypeptide chain

@article{Creighton1980CountingIN,
  title={Counting integral numbers of amino acid residues per polypeptide chain},
  author={Thomas E. Creighton},
  journal={Nature},
  year={1980},
  volume={284},
  pages={487-489}
}
Proteins have integral numbers of each of the 20 amino acids. However, all the currently accepted methods of determining this number measure the ratio of moles of amino acid residue per mole of protein. This value is rarely close to an integer, due to experimental errors in determination of the molar amounts of both amino acid residues and polypeptide chain1–3. A simple method which gives integral values of amino acid residues per polypeptide chain, independent of any other properties of the… CONTINUE READING

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