Council Lecture. Drusen and their relationship to senile macular degeneration.

  title={Council Lecture. Drusen and their relationship to senile macular degeneration.},
  author={Shirley Sarks},
  journal={Australian journal of ophthalmology},
  volume={8 2},
  • Shirley Sarks
  • Published 1980 in Australian journal of ophthalmology
This study is based on the clinico-pathological examination of 512 eyes. As senile macular degeneration developed drusen appeared to alter in consistency and become more fluid. This resulted in a spectrum of clinical appearances classified as hard, semisolid, soft or serous, and regressing. Histologically the hyaline contents of the drusen changed to a pale-staining amorphous material which electron microscopy showed to consist of vesicles. This membranous debris first appeared beneath the… CONTINUE READING
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