Coumarin-caged glycine that can be photolyzed within 3 microseconds by visible light.

@article{Shembekar2007CoumarincagedGT,
  title={Coumarin-caged glycine that can be photolyzed within 3 microseconds by visible light.},
  author={Vishakha R Shembekar and Yongli Chen and Barry K Carpenter and George P. Hess},
  journal={Biochemistry},
  year={2007},
  volume={46 18},
  pages={5479-84}
}
The synthesis and characterization of a new photolabile precursor of glycine (coumarin-caged glycine) are reported. The new compound is suitable for rapid chemical kinetic investigations of the membrane-bound neurotransmitter receptor activated by glycine. Unlike previously used caging groups for glycine, this precursor can be photolyzed rapidly and efficiently in the visible wavelength region. This allows the use of a relatively inexpensive light source. The alpha-carboxyl group of glycine was… CONTINUE READING

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