Could the serotonin theory give rise to a treatment for levodopa-induced dyskinesia in Parkinson's disease?

@article{Bzard2015CouldTS,
  title={Could the serotonin theory give rise to a treatment for levodopa-induced dyskinesia in Parkinson's disease?},
  author={Erwan B{\'e}zard and Manolo Carta},
  journal={Brain : a journal of neurology},
  year={2015},
  volume={138 Pt 4},
  pages={
          829-30
        }
}
Involuntary movements, or dyskinesias, are a debilitating complication of levodopa therapy for Parkinson’s disease, and are ultimately experienced by the vast majority of patients. In this issue of Brain, Svenningsson et al. provide evidence that oral treatment with eltoprazine, a 5-HT1A/1B receptor agonist, has beneficial antidyskinetic effects together with a favourable risk-benefit profile in Parkinson’s disease (Svenningsson et al., 2015). Currently, the only recommended add-on… CONTINUE READING
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