Could muscle deformity in children with spastic cerebral palsy be related to an impairment of muscle growth and altered adaptation?

@article{Gough2012CouldMD,
  title={Could muscle deformity in children with spastic cerebral palsy be related to an impairment of muscle growth and altered adaptation?},
  author={Martin Gough and Adam Peter Shortland},
  journal={Developmental medicine and child neurology},
  year={2012},
  volume={54 6},
  pages={495-9}
}
Skeletal muscle deformity is common in children with spastic cerebral palsy (CP), but the underlying mechanisms are unclear. This review explores some possible factors which may influence the development of muscle deformity in CP. Normal muscle function and growth appear to depend on the interaction of neuronal, endocrinal, nutritional, and mechanical factors, and also on the development of an appropriate balance between muscle protein synthesis and degradation, and between the development of… CONTINUE READING

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