Could interferon-gamma be a therapeutic target for treating heart failure?

@article{Levick2013CouldIB,
  title={Could interferon-gamma be a therapeutic target for treating heart failure?},
  author={Scott P Levick and Paul H. Goldspink},
  journal={Heart Failure Reviews},
  year={2013},
  volume={19},
  pages={227-236}
}
The cytokine interferon-gamma (IFN-γ) is the only known member of the type II family of interferons, and as such, binds to its own distinct receptor. It is important in host defense against infection, as well as adaptive immune responses. While a wide array of cytokines are known to be involved in adverse remodeling of the heart and the progression to heart failure, the role of IFN-γ is unclear. Recent evidence from clinical studies, animal models of myocarditis and hypertension, as well as… CONTINUE READING
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