Could hyperthermia with proton therapy mimic carbon ion therapy? Exploring a thermo-radiobiological rationale.

Abstract

Hyperthermia has been conventionally used in conjunction with photon beam irradiation. With a gradual increase in particle therapy facilities worldwide, this paper explores the physical, thermal and radiobiological implications of using a combination of hyperthermia with proton beam therapy. Hyperthermia is known to exhibit radiobiological features similar to those of high linear energy transfer radiation. Protons have many of the physical dose distribution properties of (12)C ion therapy. Thus, the thermo-radiobiological advantages of hyperthermia coupled with the physical dose distribution advantages of proton beams could possibly mimic (12)C ion therapy.

DOI: 10.3109/02656736.2014.963703

Cite this paper

@article{Datta2014CouldHW, title={Could hyperthermia with proton therapy mimic carbon ion therapy? Exploring a thermo-radiobiological rationale.}, author={Niloy Ranjan Datta and Emsad Puric and Ralf A. Schneider and Damien C Weber and Susanne H Rogers and Stephan Bodis}, journal={International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group}, year={2014}, volume={30 7}, pages={524-30} }