Could early antiretroviral therapy entail more risks than benefits in sub-Saharan African HIV-infected adults? A model-based analysis.

Abstract

BACKGROUND Initiation of antiretroviral therapy (ART) in all HIV-infected adults, regardless of CD4⁺ T-cell count, is a proposed strategy for reducing HIV transmission. We investigated the conditions under which starting ART early could entail more risks than benefits for patients with high CD4⁺ T-cell counts. METHODS We used a simulation model to compare… (More)
DOI: 10.3851/IMP2231

Topics

5 Figures and Tables

Cite this paper

@article{Anglaret2013CouldEA, title={Could early antiretroviral therapy entail more risks than benefits in sub-Saharan African HIV-infected adults? A model-based analysis.}, author={Xavier Anglaret and Callie A. Scott and Rochelle P. Walensky and Eric N Ouattara and Elena Losina and Raoul Moh and Jessica E. Becker and Lauren M Uhler and Christine Danel and Eug{\`e}ne Messou and Serge Paul Eholi{\'e} and Kenneth A. Freedberg}, journal={Antiviral therapy}, year={2013}, volume={18 1}, pages={45-55} }