Could A Deletion in Neuraminidase Stalk Strengthen Human Tropism of the Novel Avian Influenza Virus H7N9 in China, 2013?

@inproceedings{Chen2015CouldAD,
  title={Could A Deletion in Neuraminidase Stalk Strengthen Human Tropism of the Novel Avian Influenza Virus H7N9 in China, 2013?},
  author={Liang Chen and Feng Zhu and Chenglong Xiong and Zhijie Zhang and Lufang Jiang and Yue Chen and Genming Zhao and Qing-wu Jiang},
  booktitle={International journal of environmental research and public health},
  year={2015}
}
UNLABELLED Objective. A novel avian influenza A virus (AIV) H7N9 subtype which emerged in China in 2013 caused worldwide concern. Deletion of amino-acids 69 to 73 in the neuraminidase stalk was its most notable characteristic. This study is aimed to discuss the tropism and virulence effects of this deletion. METHODS Neuraminidase gene sequences of N9 subtype were collected from NCBI and GISAID. MEGA6.0, Stata12.0, and UCSF Chimera were employed for sequence aligning, significance testing, and… CONTINUE READING
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Early hypercytokinemia is associated with interferon-induced transmembrane protein-3 dysfunction and predictive of fatal H7N9 infection.

Proceedings of the National Academy of Sciences of the United States of America • 2014
View 1 Excerpt

http://platform

Global Initiative on Sharing Avian Influenza Database . A online
gisaid.org/epi3/frontend • 2014
View 2 Excerpts

Evolutionary characteristics of A/Hangzhou/1/2013 and source of avian influenza virus H7N9 subtype in China.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2013
View 2 Excerpts

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