Cough sensors. I. Physiological and pharmacological properties of the afferent nerves regulating cough.

@article{Canning2009CoughSI,
  title={Cough sensors. I. Physiological and pharmacological properties of the afferent nerves regulating cough.},
  author={Brendan J. Canning and Y-L Chou},
  journal={Handbook of experimental pharmacology},
  year={2009},
  volume={187},
  pages={23-47}
}
The afferent nerves regulating cough have been reasonably well defined. The selective effects of general anesthesia on C-fiber-dependent cough and the opposing effects of C-fiber subtypes in cough have led to some uncertainty about their regulation of this defensive reflex. But a role for C-fibers in cough seems almost certain, given the unique pharmacological properties of these unmyelinated vagal afferent nerves and the ability of many C-fiber-selective stimulants to evoke cough. The role of… CONTINUE READING
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