Cotard's syndrome in adolescents and young adults is associated with an increased risk of bipolar disorder.

@article{Consoli2007CotardsSI,
  title={Cotard's syndrome in adolescents and young adults is associated with an increased risk of bipolar disorder.},
  author={Ang{\`e}le Consoli and Charlotte Soultanian and Marie-Laure Tanguy and Claudine Laurent and Didier Perisse and Rogelio Luque and Germ{\'a}n E. Berr{\'i}os and David Cohen},
  journal={Bipolar disorders},
  year={2007},
  volume={9 6},
  pages={
          665-8
        }
}
OBJECTIVES To assess the effect of age at onset on the phenomenology of Cotard's syndrome (CS) as a recent study reported a high rate of occurrence of bipolar disorder (BD) in adolescents and young adults with CS followed up for > or =2 years. METHODS We reviewed all cases of CS reported since it was first described. A statistical analysis was carried out to determine the effect of age at onset on CS phenomenology. RESULTS We found 138 cases including 21 cases aged 25 years or younger. In… 
View on PubMed
speapsl.aphp.fr
35 Citations
Highly Influential Citations
2
Background Citations
14
Methods Citations
1
Results Citations
1

35 Citations

Citation Type

Citation Type

Admixture analysis of age at onset in bipolar disorder
[Bipolar episodes in adolescents: diagnostic issues and follow-up in adulthood].
Phenomenology, socio-demographic factors and outcome upon discharge of manic and mixed episodes in hospitalized adolescents
TLDR
The results suggest that severe manic and mixed episodes in adolescents with BD-I need prolonged inpatient care to improve and that socio-cultural factors and MR should be examined more closely in youth with BD.
Early interventions for youths at high risk for bipolar disorder: a developmental approach
TLDR
The aim of this article is to review the principal forms of evidence that support preventive interventions for BD in children and adolescents and the main challenges associated with these programmes.
Factor structure of Cotard’s syndrome: Systematic review of case reports
Case reports of Cotard's syndrome in Japan: a review
TLDR
The investigation of the sex, age, diagnosis, and treatment methods of patients included in case reports of Cotard’s syndrome published in Japan over a period of 35 years found no evidence of cure in two cases, and one patient responded to psychotherapy.
Towards understanding Cotard s syndrome: an overview
TLDR
Although not a separate diagnostic entity, the phenomenologic study of rare monothematic delusional disorders (such as Cotard’s syndrome) remains important to have a better understanding of the pathophysiology of delusions.
Cotard and Capgras delusions in a patient with bipolar disorder: “I’ll prove, I’m dead!”
TLDR
A patient with bipolar disorder type-2 who displayed comorbid Cotard and Capgras delusions which were most evident at the onset of menstrual periods is described.
Cotard’s Syndrome: Two Cases of Self-Starvation
TLDR
Cotard’s syndrome is a nosological and clinical entity that should not be forgotten and it is essential to provide an urgent and adequate therapeutic approach to these patients.
The ‘dead man walking’ disorder: an update on Cotard’s syndrome
TLDR
An update, as well as a putative systematization, of current views and opinions about this nosological entity in the light of the recent progress in the clinic, psychopathology and psycho-neurobiology are given.
...
1
2
3
4
...

References

SHOWING 1-10 OF 41 REFERENCES
Cotard's syndrome in adolescents and young adults: a possible onset of bipolar disorder requiring a mood stabilizer?
TLDR
Among the 14 cases reported with at least a 2-year follow-up, 13 patients (93%; 11 female) exhibited a bipolar outcome, and the use of mood stabilizers should be considered in this rare, but potentially severe, condition.
Rate and predictors of prepubertal bipolarity during follow-up of 6- to 12-year-old depressed children.
TLDR
The findings strongly support the need to educate families of children with prepubertal-onset MDD about the possibility of the emergence of manic and hypomanic symptoms to encourage early recognition and appropriate treatment.
Age at onset in bipolar I affective disorder: further evidence for three subgroups.
TLDR
There are three age-at-onset subgroups of bipolar patients, and specific familial vulnerability factors might underlie each subgroup.
Bipolar disorder at prospective follow-up of adults who had prepubertal major depressive disorder.
TLDR
High rates of switching to mania have implications for the treatment of depressed children and the authors discuss the reasons for their finding a higher rate of bipolar disorder in this outcome study than was found in the one other adult outcome study of prepubertal major depressive disorder.
Cotard's syndrome: analysis of 100 cases
TLDR
A statistical analysis has been carried out of 100 cases of Cotard's syndrome to determine how this clinical concept has fared since its inception, finding no difference was found between men and women or between underlying diagnostic categories; age seemed to increase the likelihood of developing délire des négations.
A case study of Cotard's syndrome: stages and diagnosis
TLDR
Although symptoms change according to the stage, most cases of Cotard's syndrome may belong to the affective spectrum and are probably best treated with ECT, as documented here.
Different familial transmission patterns in bipolar I disorder with onset before and after age 25.
TLDR
Segregation analysis showed that the disease is transmitted differently in early- and late-onset groups, and a non-Mendelian major gene with a polygenic component was favored while the data in the late-ONSet group were compatible with a multifactorial model.
Bipolar affective disorder and Parkinson's disease: a rare, insidious and often unrecognized association
TLDR
Five patients with Parkinson's disease and primary major psychiatric disorder meeting DSM-IV criteria for the diagnosis of bipolar affective disorder (BAD) were studied and two manic episodes occurred shortly after an increase of dopaminergic therapy and in one case rapid cyclic mood fluctuations were observed.
[Description of a case of Cotard's syndrome].
TLDR
The case of a male 61-year-old patient with Cotard's syndrome, set three years ago with depressive symptoms that did not show the specific features of the syndrome, but failed to respond fully to treatment with tricyclic antidepressants, is reported.
Bipolar illness in adolescents with major depression: clinical, genetic, and psychopharmacologic predictors in a three- to four-year prospective follow-up investigation.
TLDR
All predictors were shown to have high specificity for bipolar outcome, whereas pharmacologic hypomania and symptom cluster permitted the highest confidence of prediction, 100% and 80%, respectively.
...
1
2
3
4
5
...