Costunolide suppresses an inflammatory angiogenic response in a subcutaneous murine sponge model.

@article{Saraswati2018CostunolideSA,
  title={Costunolide suppresses an inflammatory angiogenic response in a subcutaneous murine sponge model.},
  author={Sarita Saraswati and Abdulqader A. Alhaider and Abdelgalil M Abdelgadir},
  journal={APMIS : acta pathologica, microbiologica, et immunologica Scandinavica},
  year={2018},
  volume={126 3},
  pages={257-266}
}
Costunolide is known to possess anti-inflammatory and antitumor activity, but its role in tumor angiogenesis, the key step involved in tumor growth and metastasis, and the involved molecular mechanism is still unknown. We aimed to investigate the effects of costunolide on key components of inflammatory angiogenesis in the murine cannulated sponge implant… CONTINUE READING