Costimulation molecule expression and subset distribution of blood dendritic cells in normal children and newly diagnosed pediatric leukemia and lymphoma patients.

@article{Caruso2008CostimulationME,
  title={Costimulation molecule expression and subset distribution of blood dendritic cells in normal children and newly diagnosed pediatric leukemia and lymphoma patients.},
  author={Denise A Caruso and Sarah J Fraser and Kellie Hardy and Gerlinda M Amor and Jorinde J Helmich and David Michael Ashley},
  journal={Experimental hematology},
  year={2008},
  volume={36 12},
  pages={1691-703}
}
OBJECTIVE To characterize dendritic cell (DC) numbers, subset distribution, phenotype, and costimulation molecule expression in a normal pediatric population and in a lymphoblastic malignant pretherapy pediatric population. DC are potent antigen-presenting cells and are crucial for initiating specific immune responses. MATERIALS AND METHODS We first… CONTINUE READING