Costimulation-adhesion blockade is superior to cyclosporine A and prednisone immunosuppressive therapy for preventing rejection of differentiated human embryonic stem cells following transplantation.

Abstract

RATIONALE Human embryonic stem cell (hESC) derivatives are attractive candidates for therapeutic use. The engraftment and survival of hESC derivatives as xenografts or allografts require effective immunosuppression to prevent immune cell infiltration and graft destruction. OBJECTIVE To test the hypothesis that a short-course, dual-agent regimen of two… (More)
DOI: 10.1002/stem.1501

Topics

Statistics

050100150201320142015201620172018
Citations per Year

234 Citations

Semantic Scholar estimates that this publication has 234 citations based on the available data.

See our FAQ for additional information.

  • Blog articles referencing this paper

  • Presentations referencing similar topics