Cost efficient and effective gene transfer into the human natural killer cell line, NK92.

@article{Grund2005CostEA,
  title={Cost efficient and effective gene transfer into the human natural killer cell line, NK92.},
  author={Eric M. Grund and Robin Muise-Helmericks},
  journal={Journal of immunological methods},
  year={2005},
  volume={296 1-2},
  pages={31-6}
}
Introducing genes into cells is a crucial step in many fields of basic research, as well as for the development of new drugs and therapies. Many cell types are resistant to normal methods of gene delivery, such as lipid based transfection and electroporation. Delivery to resistant cell lines can be costly or inefficient. Natural killer (NK) cells are highly resistant to transfection. We have developed a novel method to deliver exogenous genes in the NK cell line, NK92. Using a combination of… CONTINUE READING

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