Cost-effectiveness analysis of cochlear dose reduction by proton beam therapy for medulloblastoma in childhood

@inproceedings{Hirano2014CosteffectivenessAO,
  title={Cost-effectiveness analysis of cochlear dose reduction by proton beam therapy for medulloblastoma in childhood},
  author={Emi Hirano and Hiroshi Fuji and Tsuyoshi Onoe and Vinay Kumar and Hiroki Shirato and Koichi Kawabuchi},
  booktitle={Journal of radiation research},
  year={2014}
}
BACKGROUND The aim of this study is to evaluate the cost-effectiveness of proton beam therapy with cochlear dose reduction compared with conventional X-ray radiotherapy for medulloblastoma in childhood. METHODS We developed a Markov model to describe health states of 6-year-old children with medulloblastoma after treatment with proton or X-ray radiotherapy. The risks of hearing loss were calculated on cochlear dose for each treatment. Three types of health-related quality of life (HRQOL) of… CONTINUE READING