Cosmetic benefits of astaxanthin on humans subjects.

@article{Tominaga2012CosmeticBO,
  title={Cosmetic benefits of astaxanthin on humans subjects.},
  author={Kumi Tominaga and Nobuko Hongo and Mariko Karato and Eiji Yamashita},
  journal={Acta biochimica Polonica},
  year={2012},
  volume={59 1},
  pages={
          43-7
        }
}
Key MethodTwo human clinical studies were performed. One was an open-label non-controlled study involving 30 healthy female subjects for 8 weeks. Significant improvements were observed by combining 6 mg per day oral supplementation and 2 ml (78.9 μM solution) per day topical application of astaxanthin. Astaxanthin derived from the microalgae, Haematococcus pluvialis showed improvements in skin wrinkle (crow's feet at week-8), age spot size (cheek at week-8), elasticity (crow's feet at week-8), skin…
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171 Citations
Highly Influential Citations
4
Background Citations
48
Methods Citations
3
Results Citations
1

171 Citations

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References

SHOWING 1-10 OF 16 REFERENCES

Effects of astaxanthin from Haematococcus pluvialis

Astaxanthin is a natural color carotenoid found in salmon, salmon eggs, krill, and crab. Therefore, astaxanthin has been contained in the human diet for a long time. Astaxanthin from krill has been…

Cosmetic benefit of dietary supplements including astaxanthin and tocotrienol on human skin

Astaxanthin has become one of the major materials eagerly anticipated by industries for dietary supplements, and its other various specificities have been reported, including anti-inflammatory action, anti-atherosclerotic action, and inhibiting action against bladder cartinogenesis.

Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae.

The ketocarotenoid astaxanthin can be found in the microalgae Haematococcus pluvialis, Chlorella zofingiensis, and Chlorococcum sp., and the red yeast Phaffia rhodozyma. The microalga H. pluvialis…

Efficient radical trapping at the surface and inside the phospholipid membrane is responsible for highly potent antiperoxidative activity of the carotenoid astaxanthin.

Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF-kappaB activation.

Astaxanthin, probably due to its antioxidant activity, inhibits the production of inflammatory mediators by blocking NF-kappaB activation and as a consequent suppression of IKK activity and I(kappa)B-alpha degradation.

Astaxanthin Inhibits Nitric Oxide Production and Inflammatory Gene Expression by Suppressing I κ B Kinase-dependent NF-κ B Activation

The Vascular System Research Center and Department of Molecular and Cellular Biochemistry, Kangwon National University Biology, Chunchon 200-701, Korea, and Young-Myeong Kim are the main sources of inspiration for this research.

Xanthophylls as precursors of retinoids

Reductive metabolic pathways from3-dehydroretinol to retinol and from 3-deHydroretinal to retinal have been newly discovered by feeding experiments with rat and yellowtail, respectively.

Biological functions and activities of animal carotenoids

Abstract

Chemistry of carotenoid oxidation and free radical reactions

Abstract

VOLUME 10 (2006) The Effects of a Dietary Supplement Containing Astaxanthin on Skin Condition