Corynebacterium pseudotuberculosis secreted antigen-induced specific gamma-interferon production by peripheral blood leukocytes: potential diagnostic marker for caseous lymphadenitis in sheep and goats.

@article{Rebouas2011CorynebacteriumPS,
  title={Corynebacterium pseudotuberculosis secreted antigen-induced specific gamma-interferon production by peripheral blood leukocytes: potential diagnostic marker for caseous lymphadenitis in sheep and goats.},
  author={Miriam Flores Rebouças and Ricardo Dias Portela and Danielle Dantas Lima and Dan Loureiro and Bruno Lopes Bastos and L{\'i}lia Ferreira de Moura-Costa and Vera L{\'u}cia Costa Vale and Anderson Miyoshi and Vasco A. C. Azevedo and Roberto Meyer},
  journal={Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc},
  year={2011},
  volume={23 2},
  pages={
          213-20
        }
}
In the current study, the applicability of the quantification of gamma interferon (IFN-γ) levels for the detection of animals infected with Corynebacterium pseudotuberculosis and for determining caseous lymphadenitis (CLA) clinical status was evaluated. Peripheral blood leukocytes were collected from CLA nonendemic areas animals, from CLA seropositive animals without clinical signs of the disease, and from seropositive animals presenting CLA clinical signs. The leukocytes were stimulated with C… CONTINUE READING
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