Corynebacterium glutamicum as a host for synthesis and export of D-Amino Acids.

@article{Stbler2011CorynebacteriumGA,
  title={Corynebacterium glutamicum as a host for synthesis and export of D-Amino Acids.},
  author={Norma St{\"a}bler and Tadao Oikawa and Michael Bott and Lothar Eggeling},
  journal={Journal of bacteriology},
  year={2011},
  volume={193 7},
  pages={1702-9}
}
A number of d-amino acids occur in nature, and there is growing interest in their function and metabolism, as well as in their production and use. Here we use the well-established l-amino-acid-producing bacterium Corynebacterium glutamicum to study whether d-amino acid synthesis is possible and whether mechanisms for the export of these amino acids exist. In contrast to Escherichia coli, C. glutamicum tolerates d-amino acids added extracellularly. Expression of argR (encoding the broad… CONTINUE READING
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