Cortistatin vaccination--a solution to growth hormone deficiency.

  title={Cortistatin vaccination--a solution to growth hormone deficiency.},
  author={Muhammad Moaeen-ud-Din and Nosheen Malik and Yang Li Guo and Ahmad Abdul Ali and Masroor Ellahi Babar},
  journal={Medical hypotheses},
  volume={73 6},
Cortistatin and somatostatin are neuropeptides which have inhibitory effects on growth hormone through common five receptors. Although, both have inhibitory effects but, only cortistatin has direct inhibitory effects on growth hormone secretagogue and is more potent inhibitor of growth hormone than somatostatin. This control of growth hormone can be manipulated through immunoneutralization of cortistatin through cortistatin DNA vaccine rather than antibodies application. A DNA vaccine of… CONTINUE READING

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