Cortistatin modulates the expression and release of corticotrophin releasing hormone in rat brain. Comparison with somatostatin and octreotide.

@article{Tringali2012CortistatinMT,
  title={Cortistatin modulates the expression and release of corticotrophin releasing hormone in rat brain. Comparison with somatostatin and octreotide.},
  author={Giuseppe Tringali and Maria Cristina Greco and Lucia Lisi and Giacomo Pozzoli and Pierluigi Navarra},
  journal={Peptides},
  year={2012},
  volume={34 2},
  pages={353-9}
}
Cortistatin (CST) is an endogenous neuropeptide characterized by remarkable structural and functional resemblance to somatostatin (SST), both peptides sharing the ability to bind and activate all five SST receptor subtypes. Evidence is also available showing that CST exerts biological activities independently from SST, perhaps via the activation of specific receptors that remain to be fully characterized at present. Here we have investigated the effects of CST on the gene expression and release… CONTINUE READING
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Ghrelin stimulates corticotrophin - releasing factor and vasopressin gene expression in rat hypothalamus AB cells

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