Cortistatin as a therapeutic target in inflammation.

  title={Cortistatin as a therapeutic target in inflammation.},
  author={Alicia Rubio and Jes{\'u}s {\'A}vila and Luis de Lecea},
  journal={Expert opinion on therapeutic targets},
  volume={11 1},
Cortistatin (CST) is a recently discovered neuropeptide from the somatostatin gene family, named after its predominantly cortical expression and ability to depress cortical activity. CST shows many remarkable structural and functional similarities to its related neuropeptide somatostatin, or somatotropin release-inhibiting factor. However, the many physiological differences between CST and somatostatin are just as remarkable as the similarities. CST-29 has recently been shown to prevent… CONTINUE READING