Cortistatin and somatostatin mRNAs are differentially regulated in response to kainate.

@article{Calbet1999CortistatinAS,
  title={Cortistatin and somatostatin mRNAs are differentially regulated in response to kainate.},
  author={Marta Calbet and Ana Guada{\~n}o-Ferraz and Avron D. Spier and Marcin Maj and J. Gregor Sutcliffe and Ryszard Przewłocki and Luis de Lecea},
  journal={Brain research. Molecular brain research},
  year={1999},
  volume={72 1},
  pages={55-64}
}
Cortistatin (CST) is a presumptive neuropeptide that shares 11 of its 14 amino acids with somatostatin (SST). CST and SST are expressed in partially overlapping but distinct populations of cortical interneurons. In the hippocampal formation, most CST-positive cells are also positive for SST. In contrast to SST, administration of CST into the rat brain ventricles reduces locomotor activity and specifically enhances slow wave sleep. Intracerebroventricular injection of CST or SST has been shown… CONTINUE READING

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