Cortistatin--functions in the central nervous system.

  • Luis de Lecea
  • Published 2008 in Molecular and cellular endocrinology

Abstract

Cortistatin (CST) is a neuropeptide from the somatostatin (SRIF)/urotensin (UII) family named after its predominantly cortical expression and ability to depress cortical activity, which was discovered a decade ago. In vitro assays show CST is able to bind all five cloned somatostatin receptors and shares many pharmacological and functional properties with… (More)
DOI: 10.1016/j.mce.2007.12.014

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