Cortisol response to ACTH stimulation correlates with blood interleukin 6 concentration in healthy humans.

@article{arkovi2008CortisolRT,
  title={Cortisol response to ACTH stimulation correlates with blood interleukin 6 concentration in healthy humans.},
  author={Milo{\vs} P. Žarkovi{\'c} and Svetlana D Ignjatovi{\'c} and Marijana Dajak and Jasmina {\'C}iri{\'c} and Biljana Beleslin and Slavica Savic and Mirjana Stojkovi{\'c} and Petar V. Bulat and Bozo Trbojevi{\'c}},
  journal={European journal of endocrinology},
  year={2008},
  volume={159 5},
  pages={649-52}
}
OBJECTIVE Interleukin 6 (IL6) has the ability to influence each level of the hypothalamo-pituitary-adrenocortical (HPA) axis. The aim of the study was to test whether IL6 concentration correlates with the adrenal cortex response to ACTH in healthy humans. We postulated that higher basal IL6 concentration would be associated with the higher cortisol response to the stimulation. DESIGN AND METHODS Basal IL6 concentration was measured and a low dose (1 microg) ACTH test was performed to assess… CONTINUE READING