Cortisol induces apoptosis in activated B cells, not in other lymphoid cells of the common carp, Cyprinus carpio L..

@article{Weyts1998CortisolIA,
  title={Cortisol induces apoptosis in activated B cells, not in other lymphoid cells of the common carp, Cyprinus carpio L..},
  author={Franci A Weyts and Gert Flik and J. H. W. M. Rombout and B. M. Lidy Verburg-van Kemenade},
  journal={Developmental and comparative immunology},
  year={1998},
  volume={22 5-6},
  pages={551-62}
}
In mammalian T and B cells glucocorticoids (GS) regulate development and selection through induction of apoptosis; more recently GS-induced apoptosis has also been implicated in the removal of circulating, activated T and B cells following an immune response. In an earlier report we have given the first evidence for cortisol-induced apoptosis as an immune regulator in an aquatic vertebrate, the common carp. Here we report on subpopulation-specific sensitivity of carp peripheral blood leukocytes… CONTINUE READING