Cortisol in the morning and dimensions of anxiety, depression, and aggression in children from a general population and clinic-referred cohort: An integrated analysis. The TRAILS study

@article{Dietrich2013CortisolIT,
  title={Cortisol in the morning and dimensions of anxiety, depression, and aggression in children from a general population and clinic-referred cohort: An integrated analysis. The TRAILS study},
  author={Andrea Dietrich and J. Ormel and Jan K. Buitelaar and Frank C. Verhulst and Catharina Annette Hartman},
  journal={Psychoneuroendocrinology},
  year={2013},
  volume={38},
  pages={1281-1298}
}
Anxiety and depressive problems have often been related to higher hypothalamic-pituitary-adrenal (HPA)-axis activity (basal morning cortisol levels and cortisol awakening response [CAR]) and externalizing problems to lower HPA-axis activity. However, associations appear weaker and more inconsistent than initially assumed. Previous studies from the Tracking Adolescents Individual Lives Study (TRAILS) suggested sex-differences in these relationships and differential associations with specific… CONTINUE READING
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