Cortisol and dehydroepiandrosterone affect the response of peripheral blood mononuclear cells to mycobacterial antigens during tuberculosis.

@article{Mahuad2004CortisolAD,
  title={Cortisol and dehydroepiandrosterone affect the response of peripheral blood mononuclear cells to mycobacterial antigens during tuberculosis.},
  author={Carolina V. Mahuad and Mar{\'i}a Luisa Bay and Miguel Angel Farroni and Ver{\'o}nica V. Bozza and Adriana del Rey and Hugo Oscar Besedovsky and Oscar Adelmo Bottasso},
  journal={Scandinavian journal of immunology},
  year={2004},
  volume={60 6},
  pages={
          639-46
        }
}
The effect of cortisol and/or dehydroepiandrosterone (DHEA) on the immune response to antigens obtained from Mycobacterium tuberculosis was studied in vitro by using peripheral blood mononuclear cells obtained from patients at various stages of lung tuberculosis (TB) and from healthy control people (HCo). The results obtained show for the first time that addition of cortisol within concentrations of physiological range can inhibit the mycobacterial antigen-driven proliferation of cells from HCo… CONTINUE READING

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