Corticotropin-releasing hormone stimulates steroidogenesis in mouse Leydig cells.

  title={Corticotropin-releasing hormone stimulates steroidogenesis in mouse Leydig cells.},
  author={Bu Miin Huang and Douglas M. Stocco and James C. Hutson and Reid L. Norman},
  journal={Biology of reproduction},
  volume={53 3},
The actions of corticotropin-releasing hormone (CRH) on steroidogenesis in enriched preparations of mouse and rat Leydig cells were investigated. Primary cultures of purified Leydig cells as well as a Leydig tumor cell line were used in these studies. CRH had a stimulatory effect on steroid production in both isolated preparations of mouse Leydig cells (80-90% Leydig cells) and MA-10 cells (a mouse Leydig tumor cell line). In primary cultures of mouse Leydig cells, CRH was effective over a… CONTINUE READING


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