Corticotropin-releasing hormone receptor type 1-deficiency enhances hippocampal serotonergic neurotransmission: an in vivo microdialysis study in mutant mice.

@article{Penalva2002CorticotropinreleasingHR,
  title={Corticotropin-releasing hormone receptor type 1-deficiency enhances hippocampal serotonergic neurotransmission: an in vivo microdialysis study in mutant mice.},
  author={Rosana G. Penalva and Cornelia Flachskamm and Stephan Zimmermann and Wolfgang Wurst and Florian Holsboer and Johannes M. H. M. Reul and Astrid C. E. Linthorst},
  journal={Neuroscience},
  year={2002},
  volume={109 2},
  pages={253-66}
}
Corticotropin-releasing hormone plays an important role in the coordination of various responses to stress. Previous research has implicated both corticotropin-releasing hormone and the serotonergic system as causative factors in the development and course of stress-related psychiatric disorders such as major depression. To delineate the role of the corticotropin-releasing hormone receptor type 1 (CRH-R1) in the interactions between corticotropin-releasing hormone and serotonergic… CONTINUE READING
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