Corticotropin-releasing hormone receptor antagonists: an update.


The corticotropin-releasing hormone (CRH) family, CRH, CRH-related peptides and their receptors (R) play major roles in coordinating the behavioral, endocrine, autonomic, and immune responses to stress. The wide influence of the CRH system on physiologic processes in both brain and periphery implicates the respective peptides in the pathophysiology of… (More)
DOI: 10.1159/000262526