Corticotropin-releasing hormone mediates suppression of pulsatile luteinizing hormone secretion induced by activation of alpha-adrenergic receptors in the paraventricular nucleus in female rats.

@article{Tsukamura1994CorticotropinreleasingHM,
  title={Corticotropin-releasing hormone mediates suppression of pulsatile luteinizing hormone secretion induced by activation of alpha-adrenergic receptors in the paraventricular nucleus in female rats.},
  author={Hiroko Tsukamura and Shoji Nagatani and Felino R.A. Cagampang and Satoru Kawakami and Kenkou Maeda},
  journal={Endocrinology},
  year={1994},
  volume={134 3},
  pages={1460-6}
}
The present study examined which subtype of adrenergic receptor in the paraventricular nucleus (PVN) has a role in regulating pulsatile LH secretion and whether CRH mediates the effect of norepinephrine (NE) injection into the PVN on pulsatile LH secretion in ovariectomized (OVX) and ovariectomized estradiol (E2)-treated (OVX + E2) rats. All animals were OVX, and some were sc implanted with Silastic capsules containing E2 dissolved in peanut oil. One week after ovariectomy and E2 implantation… CONTINUE READING

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