Corticotropin-releasing hormone mRNA levels in the paraventricular nucleus of patients with Alzheimer's disease and depression.

@article{Raadsheer1995CorticotropinreleasingHM,
  title={Corticotropin-releasing hormone mRNA levels in the paraventricular nucleus of patients with Alzheimer's disease and depression.},
  author={F. C. Raadsheer and Joop J. Van Heerikhuize and P J Lucassen and Witte J. G. Hoogendijk and Fred J. H. Tilders and Dick F. Swaab},
  journal={The American journal of psychiatry},
  year={1995},
  volume={152 9},
  pages={1372-6}
}
OBJECTIVE Greater activity of the hypothalamic-pituitary-adrenal (HPA) axis is associated with specific neurological and psychiatric disorders, including Alzheimer's disease and depression. Hyperactivation of paraventricular corticotropin-releasing hormone (CRH) neurons may form the basis of this increased activity of the HPA axis. METHOD Activation of the CRH neurons was determined through measurement of the amount of CRH-mRNA in the paraventricular nucleus by using quantitative, in situ… CONTINUE READING
110 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 110 extracted citations

Similar Papers

Loading similar papers…