Corticotropin-releasing factor receptor type 1 mediates emotional stress-induced inhibition of food intake and behavioral changes in rats.

@article{Hotta1999CorticotropinreleasingFR,
  title={Corticotropin-releasing factor receptor type 1 mediates emotional stress-induced inhibition of food intake and behavioral changes in rats.},
  author={Masanaka Hotta and Tamotsu Shibasaki and Keiko Arai and Hiroshi Demura},
  journal={Brain research},
  year={1999},
  volume={823 1-2},
  pages={221-5}
}
We investigated whether corticotropin-releasing factor (CRF) receptor type 1 (CRFR1) is involved in emotional stress-induced inhibition of food intake and behavioral changes in rats. The inhibition of food intake and increase in locomotor activity induced by emotional stress using a communication box were reversed by both intracerebroventricular injection of alpha-helical CRF (9-41), a non-selective CRF receptor antagonist, and intraperitoneal injection of a selective non-peptidic CRFR1… CONTINUE READING

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