Corticotropin-releasing factor in the adrenal medulla.

@article{Bruhn1987CorticotropinreleasingFI,
  title={Corticotropin-releasing factor in the adrenal medulla.},
  author={Thomas O. Bruhn and William C. Engeland and Edythe L. P. Anthony and Donald S. Gann and Ivor M. D. Jackson},
  journal={Annals of the New York Academy of Sciences},
  year={1987},
  volume={512},
  pages={115-28}
}
Immunoreactive and bioactive corticotropin-releasing factor has been identified in the adrenal gland of dogs, rats and humans. Radioimmunoassay and immunohistochemical experiments have clearly demonstrated that localization of the peptide is confined to the adrenal medulla. CRF-containing cells have a characteristic appearance and are often found in close association with blood vessels. Electron microscopic studies suggest that CRF is secreted at blood vessels within the adrenal medullary… CONTINUE READING

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