Corticotropin-releasing factor activates the noradrenergic neuron system in the rat brain.

Abstract

The effect of corticotropin-releasing factor (CRF) on central noradrenaline (NA) metabolism was examined by measuring levels of the major metabolite of NA, 3-methoxy-4-hydroxy-phenylethyleneglycol sulfate (MHPG-SO4) in several rat brain regions. Various doses of CRF ranging from 0.5-10 micrograms injected ICV significantly increased MHPG-SO4 levels in… (More)

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Cite this paper

@article{Emoto1993CorticotropinreleasingFA, title={Corticotropin-releasing factor activates the noradrenergic neuron system in the rat brain.}, author={Hirofumi Emoto and M. Tanaka and Chihiro Koga and H. Yokoo and Akihiro Tsuda and M. Yoshida}, journal={Pharmacology, biochemistry, and behavior}, year={1993}, volume={45 2}, pages={419-22} }