Corticotropin releasing factor (CRF) modulates fear-induced alterations in sleep in mice.


Contextual fear significantly reduces rapid eye movement sleep (REM) during post-exposure sleep in mice and rats. Corticotropin releasing factor (CRF) plays a major role in CNS responses to stressors. We examined the influence of CRF and astressin (AST), a non-specific CRF antagonist, on sleep after contextual fear in BALB/c mice. Male mice were implanted… (More)
DOI: 10.1016/j.brainres.2009.04.017


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