Corticotropin releasing factor (CRF): studies in alcohol preferring and non-preferring rats

@article{Ehlers1992CorticotropinRF,
  title={Corticotropin releasing factor (CRF): studies in alcohol preferring and non-preferring rats},
  author={Cindy L Ehlers and Robert I. Chaplin and Tamara L Wall and Lawrence Lumeng and Ting Kai Li and Michael J. Owens and Charles B. Nemeroff},
  journal={Psychopharmacology},
  year={1992},
  volume={106},
  pages={359-364}
}
Electroencephalographic (EEG) responses to corticotropin releasing factor (CRF) as well as CRF concentrations in several brain regions were measured in two lines of rats which have been genetically selected for alcohol preferring (P) or non-preferring (NP) behaviors. Fifteen rats were implanted with chronic electrodes and EEG spectra were evaluated following intracerebroventricular (ICV) administration of CRF (0.15 nmol) or saline. P rats demonstrated a significantly increased EEG response to… CONTINUE READING

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