Corticotropin-dependent Cushing's syndrome in a patient with chronic renal failure--a rare association.

@article{Jain1993CorticotropindependentCS,
  title={Corticotropin-dependent Cushing's syndrome in a patient with chronic renal failure--a rare association.},
  author={Sanjay Jain and Vinay Sakhuja and Anil Bhansali and Krishan Lal Gupta and Radharaman Jiban Dash and Kirpal S. Chugh},
  journal={Renal failure},
  year={1993},
  volume={15 4},
  pages={563-6}
}
Corticotropin-dependent Cushing's syndrome was detected in a 32-year-old male suffering from membranous nephropathy and chronic renal failure. Cortisol dynamics revealed high basal cortisol, loss of circadian rhythm, and nonsuppressibility with low-dose dexamethasone. However, the latter was suppressible with high-dose dexamethasone. Treatment with ketoconazole led to a remarkable response both clinically and biochemically. The occurrence of Cushing's syndrome in a patient with chronic renal… CONTINUE READING

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