Corticothalamic feedback can induce hypersynchronous low-frequency rhythms in the physiologically intact thalamus

@article{Debay2001CorticothalamicFC,
  title={Corticothalamic feedback can induce hypersynchronous low-frequency rhythms in the physiologically intact thalamus},
  author={Damien Debay and Alain Destexhe and Thierry Bal},
  journal={Neurocomputing},
  year={2001},
  volume={38-40},
  pages={529-538}
}
Thalamic circuits are capable of generating oscillations of di!erent frequency and level of synchrony. However, it is not known how these oscillation types are controlled in the intact brain. Here we consider the in#uence of corticothalamic feedback onto the thalamus by using thalamic slices and computational models. Models predicted that strong activation of corticothalamic feedback should transform the normal spindle oscillations (6}10 Hz) into hypersynchronous slow (2}4 Hz) oscillations. By… CONTINUE READING
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