Corticosterone is required for the prolactin receptor gene expression in the late pregnant mouse mammary gland.

@article{Mizoguchi1997CorticosteroneIR,
  title={Corticosterone is required for the prolactin receptor gene expression in the late pregnant mouse mammary gland.},
  author={Yuiko Mizoguchi and Hiroshi Yamaguchi and Fugaku Aoki and Jumpei Enami and Senkiti Sakai},
  journal={Molecular and cellular endocrinology},
  year={1997},
  volume={132 1-2},
  pages={177-83}
}
In order to clarify the prolactin receptor (PRL-R) gene expression at lactogenesis, the levels of the long and short forms of PRL-R mRNA were determined by the competitive RT-PCR in the pregnant, lactating and ovariectomized midpregnant mouse mammary gland. Plasma concentrations of corticosterone and progesterone were determined by RIA. The long form of PRL-R mRNA level was low until 10:00 on day 18, increased 3.3-fold at 22:00 on day 18 of pregnancy and further increased to 4.6-fold at 10:00… CONTINUE READING