Corticosterone Impairs Insulin-Stimulated Translocation of GLUT4 in the Rat Hippocampus

@article{Piroli2007CorticosteroneII,
  title={Corticosterone Impairs Insulin-Stimulated Translocation of GLUT4 in the Rat Hippocampus},
  author={G. Piroli and C. Grillo and Leah R Reznikov and Sheila Adams and B. McEwen and M. Charron and L. Reagan},
  journal={Neuroendocrinology},
  year={2007},
  volume={85},
  pages={71 - 80}
}
  • G. Piroli, C. Grillo, +4 authors L. Reagan
  • Published 2007
  • Medicine, Biology
  • Neuroendocrinology
  • Background: Exposure to stress levels of glucocorticoids produces physiological responses that are characteristic of type 2 diabetes, such as peripheral insulin resistance and impairment in insulin-stimulated trafficking of glucose transporter 4 (GLUT4) in muscle and fat. In the central nervous system, stress produces neuroanatomical and neurochemical changes in the hippocampus that are associated with cognitive impairments. Methods: In view of these observations, the current studies examined… CONTINUE READING
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