Corticosteroids suppress ectopic neural discharge originating in experimental neuromas.

@article{Devor1985CorticosteroidsSE,
  title={Corticosteroids suppress ectopic neural discharge originating in experimental neuromas.},
  author={Marshall Devor and Ruth Govrin-Lippmann and Pnina Raber},
  journal={Pain},
  year={1985},
  volume={22 2},
  pages={127-37}
}
Some injured sensory fibers ending in an experimental neuroma in the rat sciatic nerve discharge spontaneously. Furthermore, many become sensitive to a range of physical and chemical stimuli. The resulting afferent barrage is thought to contribute to paresthesias and pain associated with peripheral nerve injury. We report that the development of such ectopic neuroma discharge is largely prevented when the freshly cut nerve end is treated with any of 3 commercially available corticosteroid… CONTINUE READING