Corticosteroids for the long-term treatment in multiple sclerosis.

  title={Corticosteroids for the long-term treatment in multiple sclerosis.},
  author={Alfonso Ciccone and Simone Beretta and Fabio Brusaferri and Ian Galea and Alessandra Protti and Carlo Spreafico},
  journal={The Cochrane database of systematic reviews},
BACKGROUND Short term high dose corticosteroid treatment improves symptoms and short term disability after an acute exacerbation of multiple sclerosis (MS) but it is unknown whether its long-term use can reduce the accumulation of disability. OBJECTIVES To determine the efficacy and safety of long-term corticosteroid use in MS. SEARCH STRATEGY We searched the following bibliographic databases: CENTRAL (Issue 1, 2007), MEDLINE (1966 to February 2007) and EMBASE (1980 to February 2007). In an… CONTINUE READING


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