Corticosteroids differentially regulate secretion of IL-6, IL-8, and G-CSF by a human bronchial epithelial cell line.

@article{Levine1993CorticosteroidsDR,
  title={Corticosteroids differentially regulate secretion of IL-6, IL-8, and G-CSF by a human bronchial epithelial cell line.},
  author={Stewart J. Levine and Pierre Lariv{\'e}e and Carolea Logun and Craig Angus and James H. Shelhamer},
  journal={The American journal of physiology},
  year={1993},
  volume={265 4 Pt 1},
  pages={L360-8}
}
Human airway epithelial cells play an active role in modulating airway inflammation by elaborating a variety of proinflammatory molecules, including cytokines. The purpose of this study was to define the role of corticosteroids in the regulation of cytokine gene transcription and secretion by human bronchial epithelial cells. In particular, we assessed whether dexamethasone was capable of inhibiting the tumor necrosis factor-alpha (TNF-alpha)-mediated secretion of interleukin-6 (IL-6… CONTINUE READING

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