Corticosteroids and wound healing: clinical considerations in the perioperative period.

@article{Wang2013CorticosteroidsAW,
  title={Corticosteroids and wound healing: clinical considerations in the perioperative period.},
  author={Audrey S. Wang and Ehrin J Armstrong and April W Armstrong},
  journal={American journal of surgery},
  year={2013},
  volume={206 3},
  pages={
          410-7
        }
}
BACKGROUND Determining whether systemic corticosteroids impair wound healing is a clinically relevant topic that has important management implications. METHODS We reviewed literature on the effects of corticosteroids on wound healing from animal and human studies searching MEDLINE from 1949 to 2011. RESULTS Some animal studies show a 30% reduction in wound tensile strength with perioperative corticosteroids at 15 to 40 mg/kg/day. The preponderance of human literature found that high-dose… CONTINUE READING

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