Corticosteroids, 11beta-hydroxysteroid dehydrogenase isozymes and the rabbit choroid plexus.

@article{Sinclair2007Corticosteroids1D,
  title={Corticosteroids, 11beta-hydroxysteroid dehydrogenase isozymes and the rabbit choroid plexus.},
  author={Alexandra J Sinclair and Claire Uchechukwu Onyimba and Pamela Khosla and Neelima Vijapurapu and J W Tomlinson and Michael A. Burdon and Paul Michael. Stewart and Philip Ian Murray and Elizabeth Anne Walker and Saaeha Rauz},
  journal={Journal of neuroendocrinology},
  year={2007},
  volume={19 8},
  pages={
          614-20
        }
}
The epithelial cells of the choroid plexus (CP) are responsible for cerebrospinal fluid (CSF) secretion into the ventricles of the brain. The balance between CSF production and drainage, in part, facilitates a normal intracranial pressure. The secretion of Na(+) and anions by the CP creates an osmotic gradient driving water into the ventricles. This is opposite to classical Na(+) transporting tissues, such as the kidney, where Na(+) and water reabsorption is mediated by 11beta-hydroxysteroid… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 17 CITATIONS

Metabolic Concepts in Idiopathic Intracranial Hypertension and Their Potential for Therapeutic Intervention

  • Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • 2018
VIEW 1 EXCERPT
CITES BACKGROUND