Corticosteroid therapy in avian muscular dystrophy: evaluation by magnetic resonance relaxation times.

@article{Misra1988CorticosteroidTI,
  title={Corticosteroid therapy in avian muscular dystrophy: evaluation by magnetic resonance relaxation times.},
  author={Lalith K. Misra and R K Entrikin},
  journal={Experimental neurology},
  year={1988},
  volume={102 2},
  pages={217-20}
}
Genetically dystrophic chicks (line 413) were administered 0.3 mg/kg dexamethasone (DEX), a corticosteroid, from 2 to 28 days ex ovo. Diluent-injected dystrophic and normal (line 412) chicks served as controls. The effects of DEX on muscle function were evaluated weekly by the exhaustion score (ES) method. Proton magnetic resonance relaxation times, T1 and T2, of excised pectoral muscles of all chicks were measured at 31 days of age. There were two measurable components of T1 and T2 relaxation… CONTINUE READING